Benzoic acid, 2-bromo-5-hydroxy-4-methoxy-

Benzoic acid, 2-bromo-5-hydroxy-4-methoxy- - Names and Identifiers

Name	5-bromo-3-(difluoromethoxy)pyridin-2-amine
Synonyms	6-Bromoisovanillicacid 6-Bromoisovanillic acid 2-Bromo-5-hydroxy-4-methoxybenzoicacid 2-Bromo-5-Hydroxy-4-Methoxybenzoic Acid 2-bromo-4-mehtoxyl-5-hydroxybenzoic acid 2-bromo-4-mehtoxyl-5-hydroxybenzoic acid, 2-Amino-3-Difluoromethoxy-5-Bromopyridine 2-AMino-5-broMo-3-difluoroMethoxypyridine 5-bromo-3-(difluoromethoxy)pyridin-2-amine Benzoic acid, 2-bromo-5-hydroxy-4-methoxy-
CAS	947249-13-0 121936-68-3 98347-41-3

Benzoic acid, 2-bromo-5-hydroxy-4-methoxy- - Physico-chemical Properties

Molecular Formula	C8H7BrO4
Molar Mass	247.04
Density	1.757
Boling Point	367℃
Flash Point	176℃
pKa	3.00±0.10(Predicted)
Storage Condition	2-8 ℃, dark
Physical and Chemical Properties	Appearance brown powder

Benzoic acid, 2-bromo-5-hydroxy-4-methoxy- - Introduction

5-bromo-3-(difluoromethoxy)pyridin-2-amine is an organic compound with the chemical formula C7H5BrF2N2O. It is a white solid with a special smell. The following is a detailed description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White solid
-relative molecular mass: 257.03g/mol
-melting point: 84-88 ℃
-Boiling point: 318.1±35.0 ℃
-Density: 1.9±0.1g/cm3
-Refractive Index: 1.551
-Stability: Stable at room temperature, but should be away from strong acids, strong alkalis and oxidants.

Use:
5-bromo-3-(difluoromethoxy)pyridin-2-amine can be used in the field of organic synthesis and medicine. Due to its unique structure and chemical properties, it is often used as an intermediate in the synthesis of other organic compounds. It is also used as an important part of drug development.

Preparation Method:
5-bromo-3-(difluoromethoxy)pyridin-2-amine can be prepared by the following steps:
1. First, when bromoalkane and pyridine are reacted, a bromine atom is introduced.
2. Then, difluoromethoxy is introduced into the obtained compound, which can be prepared by reacting with difluoromethoxy chloride.
3. Finally, the resulting product is reacted with amine to obtain 5-bromo-3-(difluoromethoxy)pyridin-2-amine.

Safety Information:
5-bromo-3-(difluoromethoxy)pyridin-2-amine need to pay attention to the following matters during use and storage:
-It may be irritating to the skin and eyes. When in contact, wash it with plenty of water immediately and seek medical help.
-Avoid inhalation or ingestion during use, and take respiratory protection and protective measures, such as wearing a protective mask and gloves, if necessary.
-Store the compound properly and keep it away from fire and high temperatures.
-When handling this compound, please follow appropriate laboratory safety procedures and ensure adequate ventilation.

Last Update：2024-04-09 21:04:16